Monday, September 17, 2012

science publication

This is not running related, but it's very exciting news and I wanted to share.

I work at a research laboratory. Mostly, I do bench work in cell biology and immunohistochemistry. For the past 2 year I have been working simultaneously on 2 projects at work. One is for my thesis on BPA and the other is for the lab about a condition known as CVOD (corporal vascular-occlusive disorder)

The CVOD project was published in the Journal of Sexual Medicine and my name is on it :).

Separate or Combined Treatments with Daily Sildenaļ¬l, Molsidomine, or Muscle-Derived Stem Cells Prevent Erectile Dysfunction in a Rat Model of Cavernosal Nerve Damage  
  • Istvan Kovanecz PhD1,2
  • Steve Rivera MD1,
  • Gaby Nolazco MS1,3
  • Dolores Vernet PhD1,
  • Denesse Segura BS1,4
  • Sahir Gharib BS1,4,
  • Jacob Rajfer MD1,2
  • Nestor F. Gonzalez-Cadavid PhD1,2,3,*


    Introduction.  Long-term daily administration of phosphodiesterase type 5 (PDE5) inhibitors in the rat prevents or reverses corporal veno-occlusive dysfunction (CVOD) and smooth muscle cell (CSMC) loss and fibrosis, in both aging and bilateral cavernosal nerve resection (BCNR) models for erectile dysfunction. In the aging rat model, corporal implantation of skeletal muscle-derived stem cells (MDSC) reverses CVOD. Nitric oxide (NO) and cyclic guanosine monophosphate can modulate stem cell lineage.
    What's your job?
    Do you like it?

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